Effects of omega-3 supplementation on muscle mass growth: an umbrella review of systematic reviews of randomised controlled trials

Abstract

The article examines the effect of omega-3 supplements on muscle growth. The effect of omega-3 supplementation on muscle mass growth is a hot topic of interest to athletes, fitness enthusiasts and researchers. Although individual studies and reviews are available, there is a lack of synthesis and analysis of the results of multiple randomized controlled trials on this topic. This creates uncertainty regarding the efficacy of omega-3 for increasing muscle mass. Purpose. To conduct an umbrella review of systematic reviews of randomized controlled trials to assess the effects of omega-3 supplementation on muscle mass growth and to identify general conclusions and recommendations. Methods. A search for systematic reviews in major databases including PubMed, Cochrane Library and Epistemonikos was conducted using relevant keywords. Suitable reviews highlighting the effects of omega-3 on muscle growth were selected. Conclusion. Systematic reviews of critically low quality provide conflicting evidence. There is currently no evidence to recommend omega-3 as a supplement to stimulate muscle growth in athletes and physically active individuals.